GEO series

Perinatal dysfunction of innate immunity in cystic fibrosis

GSE277489 Sus scrofa; Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/11/30 Platform GPL30173Platform GPL32549

Summary

The study aimed to compare the gene expression profiles at a single cell level in peripheral blood (human&pig), lung-derived (pig), bone marrow (pig) mononuclear cells (MNC) between subjects with cystic fibrosis (CF) and disease controls (WT).

Published in

Jaudas F, Bartenschlager F, Shashikadze B et al. · Science translational medicine 2025 · PMID 39841805 · doi:10.1126/scitranslmed.adk9145

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Download

Direct links to NCBI, no account and no request form: the whole study as GSE277489_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Whole study · RAW.tar ↓ Series matrix ↓ All supplementary files ↗ Raw reads on ENA ↗

Also filed as BioProject PRJNA1162510 and SRA study SRP533394. Searching any of these in the dataset finder brings you back here.

NCBI GEO page ↗ Paper (PMID 39841805) ↗

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