GEO series
Effect of p.E475G mutation in the PNPT1 gene on 293T global transcriptome
GSE277568
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2024/10/07
GPL30882
Summary
We genereted via genome editing 293T cell lines with the heterozygous and homozygous nucleotide substitution c.1424A>G in the PNPT1 gene (namely EK81 and EK81.8, respectively), causing the amino acidic variation p.E475G, and studied their transcriptomes before and after 6 hours of treatment with 1 µM staurosporine to induce apoptosis
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Paper (PMID 41255389) ↗
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