GEO series
Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD
GSE277571
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2025/09/09
GPL24676
Summary
RNAsequencing in three subcellular fractions: cytosolic, nuclear and insoluble from vehicle-treated cells and Dox-treated cells that induces the expression of the expanded (A16) PABPN1. The goal of this study was to demonstrate PABPN1 function in A16 cells, and to identify RNA accummulation in each fraction. This allows the identification of molecular signatures.
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Paper (PMID 40901980) ↗
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