GEO series
Uptake of alpha-synuclein preformed fibrils is suppressed by inflammation and induces an aberrant phenotype in human microglia
GSE277636
Homo sapiens
Expression profiling by high throughput sequencing
24 samples
2024/10/22
GPL18573
Summary
To detect the microglial mRNA signature whilst phagocytosing alphasynuclein preformed fibrils (αSyn PFFs) with or without inflammatory stimulus, we treated the healthy control microglia with IFNγ (20ng/ml) 28h and αSyn PFFs (0.5µM) 4h
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Paper (PMID 39435593) ↗
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