Tumor suppresson protein p53 governs human trophoblast lineage development II
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 12 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Tumor suppressor protein p53 governs human trophoblast lineage developmentCell reports · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277759_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1163894 and SRA study SRP534076. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 12 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8529004 WT, Input 1 WT, Input
- GSM8529005 KO, Input 1 KO, Input
- GSM8529006 WT, p53, ChIP, rep1 WT, p53, ChIP,
- GSM8529007 WT, p53, ChIP, rep2 WT, p53, ChIP,
- GSM8529008 KO, p53, ChIP, rep1 KO, p53, ChIP,
- GSM8529009 KO, p53, ChIP, rep2 KO, p53, ChIP,
- GSM8529010 WT, H3K27ac, ChIP, rep1 WT, H3K27ac, ChIP,
- GSM8529011 WT, H3K27ac, ChIP, rep2 WT, H3K27ac, ChIP,
- GSM8529012 KO, H3K27ac, ChIP, rep1 KO, H3K27ac, ChIP,
- GSM8529013 KO, H3K27ac, ChIP, rep2 KO, H3K27ac, ChIP,
- GSM8529014 WT, Input 2 WT, Input
- GSM8529015 KO, Input 2 KO, Input
- GSM8529016 WT, H3K4me3, ChIP, rep1 WT, H3K4me3, ChIP,
- GSM8529017 WT, H3K4me3, ChIP, rep2 WT, H3K4me3, ChIP,
- GSM8529018 KO, H3K4me3, ChIP, rep1 KO, H3K4me3, ChIP,
- GSM8529019 KO, H3K4me3, ChIP, rep2 KO, H3K4me3, ChIP,
- GSM8529020 WT, H3K27me3, ChIP, rep1 WT, H3K27me3, ChIP,
- GSM8529021 WT, H3K27me3, ChIP, rep2 WT, H3K27me3, ChIP,
- GSM8529022 KO, H3K27me3, ChIP, rep1 KO, H3K27me3, ChIP,
- GSM8529023 KO, H3K27me3, ChIP, rep2 KO, H3K27me3, ChIP,
- GSM8529024 WT, ATAC, rep1 WT, ATAC,
- GSM8529025 WT, ATAC, rep2 WT, ATAC,
- GSM8529026 KO, ATAC, rep1 KO, ATAC,
- GSM8529027 KO, ATAC, rep2 KO, ATAC,
- GSE289805 Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response [ChIP-seq/ATAC-seq] 126 samples shares protein, lineage
- GSE268946 RNA-binding proteins DND1 and NANOS3 coordinately suppress SOX4 in processing bodies for restricting the entry of germ cell lineage 36 samples shares protein, lineage
- GSE239888 ChIP-seq of human embryonic stem cells (hESCs) overexpressed with Monkeypox viral proteins H3L and A29L 19 samples shares protein
- GSE266194 Ectopic expression of DNMT3L in human trophoblast stem cells restores features of the placental methylome [ChIP-seq] 15 samples shares trophoblast
- GSE281165 TFE3 fusion oncoprotein condensates drive epigenetic reprogramming and cancer progression [CUT&RUN] 43 samples shares protein
- GSE252630 Apolipoprotein L1 is a tumor suppressor in clear cell renal cell carcinoma metastasis 36 samples shares protein
- GSE296647 Indirect identification of genomic G-quadruplexes via a small protein probe that specifically recognizes C-rich single-stranded DNA 24 samples shares protein
- GSE295019 Lysine Methylpropionylation, a Hybrid Post-Translational Modification Mediated by p300/PCAF Couples Metabolic Dynamics with Protein Function 16 samples shares protein
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.