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Cis-regulatory elements driving motor neuron-selective viral payload expression within the mammalian spinal cord

GSE278180 Mus musculus (mouse) ChIP-seq / ATAC-seq (genome binding and open chromatin) 10 samples Submitted 2024/11/16 Platform GPL19057
At a glance

ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 10 samples

What it is
ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
Organism
Mus musculus (mouse)
Samples
10 samples
Data you can get
A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Paper
Cis-regulatory elements driving motor neuron-selective viral payload expression within the mammalian spinal cordProceedings of the National Academy of Sciences of the United States of America · 2024
Summary (written by the submitters)
Bulk RNA-seq and ATAC-seq of immunopurified CHAT+ and immunodepleted CHAT- nuclei of murine spinal cord
Published in
Cis-regulatory elements driving motor neuron-selective viral payload expression within the mammalian spinal cord
Nagy MA, Price S, Wang K et al. · Proceedings of the National Academy of Sciences of the United States of America 2024 · PMID 39602276 · doi:10.1073/pnas.2418024121
This dataset
Download · which file do I need?

Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.

1 · Just have a look

Processed table

The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.

2 · Re-analyse it

Supplementary files

The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278180_RAW.tar (it can run to tens of gigabytes).

3 · Start from the raw reads

Raw sequencing reads

The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.

What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.

Also filed as BioProject PRJNA1165819 and SRA study SRP535131. Searching any of these in the dataset finder brings you back here.

Samples in this study

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