Identification of RNAs that can accept assembly of an Sm-protein ring
Single-nucleus RNA-seq · mouse · 39 samples
- What it is
- Single-nucleus RNA-seqGene activity measured in individual nuclei (used when whole cells are hard to isolate, for example from frozen tissue). Read from the summary: GEO's own type field only says 'expression profiling by sequencing', so confirm it in the paper.
- Organism
- Mus musculus (mouse)
- Samples
- 39 samples: 39 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Sm-site containing mRNAs can accept Sm-rings and are downregulated in Spinal Muscular AtrophyNucleic acids research · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278538_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1167748 and SRA study SRP536055. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 39 sample titles: 39 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8548423 Human polyA-RNA 1 (hr1)
- GSM8548424 Human polyA-RNA 2 (hr2)
- GSM8548425 Human polyA-RNA 3 (hr3)
- GSM8548426 Mouse polyA-RNA 1 (mr1)
- GSM8548427 Mouse polyA-RNA 2 (mr2)
- GSM8548428 Mouse polyA-RNA 3 (mr3)
- GSM8548429 Human Sm-RIP 1 (hx1)
- GSM8548430 Human Sm-RIP 2 (hx2)
- GSM8548431 Human Sm-RIP 3 (hx3)
- GSM8548432 Mouse Sm-RIP 1 (mx1)
- GSM8548433 Mouse Sm-RIP 2 (mx2)
- GSM8548434 Mouse Sm-RIP 3 (mx3)
- GSM8548435 Modified Sm-RIP human extract, mouse polyA-RNA 1 (hxmr1)
- GSM8548436 Modified Sm-RIP human extract, mouse polyA-RNA 2 (hxmr2)
- GSM8548437 Modified Sm-RIP human extract, mouse polyA-RNA 3 (hxmr3)
- GSM8548438 Modified Sm-RIP mouse extract, human polyA-RNA 1 (mxhr1)
- GSM8548439 Modified Sm-RIP mouse extract, human polyA-RNA 2 (mxhr2)
- GSM8548440 Modified Sm-RIP mouse extract, human polyA-RNA 3 (mxhr3)
- GSM8548441 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP 1 (hxmra1)
- GSM8548442 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP 2 (hxmra2)
- GSM8548443 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP 3 (hxmra3)
- GSM8548444 Modified Sm-RIP mouse extract, human polyA-RNA, +ATP 1 (mxhra1)
- GSM8548445 Modified Sm-RIP mouse extract, human polyA-RNA, +ATP 2 (mxhra2)
- GSM8548446 Modified Sm-RIP mouse extract, human polyA-RNA, +ATP 3 (mxhra3)
- GSM8974308 Human cytoplasmic RNA 1 (hc1)
- GSM8974309 Human cytoplasmic RNA 2 (hc2)
- GSM8974310 Human cytoplasmic RNA 3 (hc3)
- GSM8974311 Human SmB Sm-RIP, stringent washing 1 (hbs1)
- GSM8974312 Human SmB Sm-RIP, stringent washing 2 (hbs2)
- GSM8974313 Human SmB Sm-RIP, stringent washing 3 (hbs3)
- GSM8974314 Human Y12 Sm-RIP, stringent washing 1 (hys1)
- GSM8974315 Human Y12 Sm-RIP, stringent washing 2 (hys2)
- GSM8974316 Human Y12 Sm-RIP, stringent washing 3 (hys3)
- GSM8974317 Modified Sm-RIP human extract, mouse polyA-RNA, stringent washing 1 (hxmrs1)
- GSM8974318 Modified Sm-RIP human extract, mouse polyA-RNA, stringent washing 2 (hxmrs2)
- GSM8974319 Modified Sm-RIP human extract, mouse polyA-RNA, stringent washing 3 (hxmrs3)
- GSM8974320 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP, stringent washing 1 (hxmras1)
- GSM8974321 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP, stringent washing 2 (hxmras2)
- GSM8974322 Modified Sm-RIP human extract, mouse polyA-RNA, +ATP, stringent washing 3 (hxmras3)
- GSE252442 DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs 134 samples shares rnas
- GSE248279 m6A is decoded by modified tRNAs to coordinate mRNA decay. 89 samples shares rnas
- GSE249713 An atlas of small non-coding RNAs in Human Preimplantation Development 1385 samples shares rnas
- GSE252810 Chrom-seq Identifies RNAs at Chromatin Marks 86 samples shares rnas
- GSE201602 RNAseq data from myotubes after treatment with iAM373 in vitro 80 samples shares rnas
- GSE252807 Chrom-seq Identifies RNAs at Chromatin Marks [Chrom_and_RNA_seq] 47 samples shares rnas
- GSE333740 Human HN-SCC-151 HPV-negative head and neck squamous cell carcinoma cells treated with DMSO or the SUV420H1 inhibitor A-196/siNC (control) or siSUV420H1 siRNAs. 45 samples shares rnas
- GSE262385 U4 inhibits premature cleavage and polyadenylation of pre-mRNAs 42 samples shares rnas
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.