Drosha loss drives pineoblastoma by upregulating Ccnd2 [RNA-seq of Dicer1 tumors]
RNA-seq (gene expression) · mouse · 3 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 3 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- An imbalance between proliferation and differentiation underlies the development of microRNA-defective pineoblastomaGenes & development · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278579_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1167817 and SRA study SRP536121. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 3 more — browse all 3 samples with per-sample file links →
- GSE255911 Drosha loss drives pineoblastoma by upregulating Ccnd2 [RNA-seq of Drosha and Rb1 tumors] 6 samples shares ccnd2, pineoblastoma, upregulating, rna-seq, drosha, drives, loss
- GSE255907 Drosha loss drives pineoblastoma by upregulating Ccnd2 [RNA-seq of palbociclib treatment] 4 samples shares ccnd2, pineoblastoma, upregulating, rna-seq, drosha, drives, loss
- GSE255906 Drosha loss drives pineoblastoma by upregulating Ccnd2 [RNAseq of brain, Drosha tumor, and pineal gland] 9 samples shares ccnd2, pineoblastoma, upregulating, drosha, drives, loss
- GSE255910 Drosha loss drives pineoblastoma by upregulating Ccnd2 [RNAseq of ceritinib treatment] 4 samples shares ccnd2, pineoblastoma, upregulating, drosha, drives, loss
- GSE255914 Drosha loss drives pineoblastoma by upregulating Ccnd2 64 samples shares ccnd2, pineoblastoma, upregulating, drosha, drives, loss
- GSE255908 Drosha loss drives pineoblastoma by upregulating Ccnd2 [CUT&RUN] 10 samples shares ccnd2, pineoblastoma, upregulating, drosha, drives, loss
- GSE255905 Drosha loss drives pineoblastoma by upregulating Ccnd2 [ATAC-seq] 9 samples shares ccnd2, pineoblastoma, upregulating, drosha, drives, loss
- GSE278346 CEBPB drives endothelial pathological phenotype and promotes atherosclerosis by directly upregulating TGFBR1 expression [scRNA-seq] 3 samples shares upregulating, rna-seq, drives
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.