Growth signaling promotes H2A.Z deposition by SRCAP to sustain somatic tissue regeneration [RNA-Seq]
RNA-seq (gene expression) · human · 42 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 42 samples: 31 distinct titles, 5 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Skin Epidermal Progenitor Maintenance by the SRCAP-H2A.Z Axis Downstream to Extracellular Signal-Regulated Kinase and mTOR SignalingThe Journal of investigative dermatology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278641_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1168139 and SRA study SRP536293. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 42 sample titles: 31 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8551791 Control 1 [RNA-seq]
- GSM8551792 Control 2 [RNA-seq]
- GSM8551793 SRCAP shRNA1 [RNA-seq]
- GSM8551794 SRCAP shRNA3 [RNA-seq]
- GSM8551795 SRCAP shRNA4 [RNA-seq]
- GSM8551796 SRCAP shRNA5 [RNA-seq]
- GSM8551797 Control 1b [RNA-seq]
- GSM8551798 Control 2b [RNA-seq]
- GSM8551799 H2AZ1 shRNA1 [RNA-seq]
- GSM8551800 H2AZ1 shRNA2 [RNA-seq]
- GSM8551801 H2AZ1 shRNA3 [RNA-seq]
- GSM8551802 H2AZ1 shRNA4 [RNA-seq]
- GSM8551803 Control 1c [RNA-seq]
- GSM8551804 Control 2c [RNA-seq]
- GSM8551805 H2AZ2 shRNA1 [RNA-seq]
- GSM8551806 H2AZ2 shRNA2 [RNA-seq]
- GSM8551807 H2AZ2 shRNA3 [RNA-seq]
- GSM8551808 H2AZ2 shRNA4 [RNA-seq]
- GSM8551809 Control 1d [RNA-seq]
- GSM8551810 Control 2d [RNA-seq]
- GSM8551811 H2AZ1 shRNA1 + H2AZ2 shRNA1 [RNA-seq]
- GSM8551812 H2AZ1 shRNA2 + H2AZ2 shRNA2 [RNA-seq]
- GSM8551813 H2AZ1 shRNA3 + H2AZ2 shRNA3 [RNA-seq]
- GSM8551814 H2AZ1 shRNA4 + H2AZ2 shRNA4 [RNA-seq]
- GSM8801059 DF control 1 - h2az1
- GSM8801060 DF control 2 - h2az1
- GSM8801061 DF H2AZ1 sh1
- GSM8801062 DF H2AZ1 sh2
- GSM8801063 DF H2AZ1 sh3
- GSM8801064 DF H2AZ1 sh4
- GSM8801065 DF control 1 - h2az2
- GSM8801066 DF control 2 - h2az2
- GSM8801067 DF H2AZ2 sh1
- GSM8801068 DF H2AZ2 sh2
- GSM8801069 DF H2AZ2 sh3
- GSM8801070 DF H2AZ2 sh4
- GSM8801071 DF control 1 - srcap
- GSM8801072 DF control 2 - srcap
- GSM8801073 DF SRCAP sh1
- GSM8801074 DF SRCAP sh3
+ 2 more — browse all 42 samples with per-sample file links →
- GSE278642 Growth signaling promotes H2A.Z deposition by SRCAP to sustain somatic tissue regeneration [ChIP-Seq] 30 samples shares srcap, h2a, regeneration, deposition, promotes, sustain, somatic
- GSE310170 Embryonic stem cell factors DPPA2/4 amplify active H3K4me3-H2AK119ub chromatin domains in non-small cell lung cancer (RNA-seq) 93 samples shares h2a, rna-seq
- GSE252447 RING1 missense variants reveal sensitivity of DNA damage repair to H2A monoubiquitination dosage during neurogenesis [bulk RNA-seq] 15 samples shares h2a, rna-seq
- GSE281128 Recognition of ubiquitinated histone H2A constitutes a treatment target for RSF1-driven ovarian cancer [RNA-seq] 13 samples shares h2a, rna-seq
- GSE229398 PGE2 alters chromatin through H2A.Zvariant enhancer nucleosome modification to promote hematopoietic stem cell fate (RNA-Seq) 10 samples shares h2a, rna-seq
- GSE252449 RING1 missense variants reveal sensitivity of DNA damage repair to H2A monoubiquitination dosage during neurogenesis [scRNA-seq] 7 samples shares h2a, rna-seq
- GSE303932 Regional Conservation and Transcriptional Regulation of Tumor-Associated Genes by macroH2A1 Deposition in Mammalian Cells 12 samples shares h2a, deposition
- GSE292167 SRCAP mutation promotes cutatneous squamous cell carcinoma invasion [ChIP-Seq] 8 samples shares srcap, promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.