Screening and Modeling of LUAD-Associated Predictive and Prognostic Genes Based on Multi-Omics Data

LUAD is widespread worldwide with onset mainly in the low-grade stage due to early screen. However, the ambiguity surrounding small-sized nodules often leads to hesitation in deciding between surgery and surveillance. Liquid biopsy which leverages the cell-free RNA (cfRNA) shows excellent classification performance among disease groups in addition to the non-invasive feature. This research utilizes liquid biopsy to construct an effective screening system to aid with the further differentiation of benign diseases from lung cancers.