Interplay between Genetic Variation and Nutrition Challenge Controls Hepatic Diurnal Rhythms [RNA-seq]
RNA-seq (gene expression) · mouse · 108 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 108 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Genetics-nutrition interactions control diurnal enhancer-promoter dynamics and liver lipid metabolismCell metabolism · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278920_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1169622 and SRA study SRP536901. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 108 more — browse all 108 samples with per-sample file links →
- GSE278921 Interplay between Genetic Variation and Nutrition Challenge Controls Hepatic Diurnal Rhythms [ChIP-seq] 13 samples shares interplay, variation, nutrition, challenge, controls, genetic, hepatic, diurnal
- GSE272206 Natural genetic variation in wild-derived mice controls host survival and transcriptional responses during endotoxic shock 24 samples shares variation, controls, genetic
- GSE285231 Systems genetics reveals the influence of eQTLs in mouse embryonic stem cells on transcriptional variation later in differentiated neural progenitor cells 186 samples shares variation, genetic
- GSE281149 Genetic variation in the anaphase promoting complex modulates fertility and chromosome alignment defects in the absence of KIF18A 60 samples shares variation, genetic
- GSE270509 In vivo CRISPR screen reveals interplay of epigenetic regulators underlies kinetics of hepatobiliary reprogramming [RNA-Seq] 27 samples shares interplay, genetic
- GSE246799 Epigenetic recording of stimulation history reveals BLIMP1-BACH2 balance in determining memory B cell fate upon recall challenge (RNA-Seq) 24 samples shares challenge, genetic
- GSE281686 Transcription factor occupancy is affected by genetic variation in the white adipose tissue of C57BL6/j and 129S1/SvImJ mice [RNA-seq] 24 samples shares variation, genetic
- GSE263794 Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown 16 samples shares variation, diurnal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.