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Pre-existing intratumoral stem-like CD8+ T-Cells drive radiotherapy-induced tumor control

GSE279242 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/03/24 Platform GPL34290Platform GPL24247
Summary
To evaluate how intratumoral CD8+ T-cells are influenced by radiotherapy, we performed single-cell RNA sequencing of CD8+ T-cells sorted from MC38-OVA tumors 6 days after radiotherapy (single dose, 20Gy).
Published in
Pre-existing intratumoral stem-like CD8(+) T cells drive radiotherapy-induced tumor immunity
Köksal H, Herbst M, Perreira P et al. · Cell reports 2025 · PMID 40215165 · doi:10.1016/j.celrep.2025.115566
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Also filed as BioProject PRJNA1171467 and SRA study SRP537813. Searching any of these in the dataset finder brings you back here.

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