Human A549 and MRC5 Cell Response to HCoV-229E Infection
RNA-seq (gene expression) · human · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples: 24 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279271_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1171767 and SRA study SRP537929. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 24 sample titles: 24 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8565586 PPI A549 229 RNA, Mock Well 1 RNA 24hr
- GSM8565587 PPI A549 229 RNA, Mock Well 2 RNA 24hr
- GSM8565588 PPI A549 229 RNA, Mock Well 3 RNA 24hr
- GSM8565589 PPI A549 229 RNA, Mock Well 4 RNA 24hr
- GSM8565590 PPI A549 229 RNA, Mock Well 5 RNA 24hr
- GSM8565591 PPI A549 229 RNA, Mock Well 6 RNA 24hr
- GSM8565592 PPI A549 229 RNA, 229 Well 1 RNA 24hr
- GSM8565593 PPI A549 229 RNA, 229 Well 2 RNA 24hr
- GSM8565594 PPI A549 229 RNA, 229 Well 3 RNA 24hr
- GSM8565595 PPI A549 229 RNA, 229 Well 4 RNA 24hr
- GSM8565596 PPI A549 229 RNA, 229 Well 5 RNA 24hr
- GSM8565597 PPI A549 229 RNA, 229 Well 6 RNA 24hr
- GSM8565598 PPI MRC5 229 RNA, Mock Well 1 RNA 24hr
- GSM8565599 PPI MRC5 229 RNA, Mock Well 2 RNA 24hr
- GSM8565600 PPI MRC5 229 RNA, Mock Well 3 RNA 24hr
- GSM8565601 PPI MRC5 229 RNA, Mock Well 4 RNA 24hr
- GSM8565602 PPI MRC5 229 RNA, Mock Well 5 RNA 24hr
- GSM8565603 PPI MRC5 229 RNA, Mock Well 6 RNA 24hr
- GSM8565604 PPI MRC5 229 RNA, 229 Well 1 RNA 24hr
- GSM8565605 PPI MRC5 229 RNA, 229 Well 2 RNA 24hr
- GSM8565606 PPI MRC5 229 RNA, 229 Well 3 RNA 24hr
- GSM8565607 PPI MRC5 229 RNA, 229 Well 4 RNA 24hr
- GSM8565608 PPI MRC5 229 RNA, 229 Well 5 RNA 24hr
- GSM8565609 PPI MRC5 229 RNA, 229 Well 6 RNA 24hr
- GSE292720 Transcriptomic profiling of baricitinib effects on host immune response to RVFV infection in A549 cells and organoids 24 samples shares a549
- GSE310262 West Nile virus and Zika virus infections induce aggresome formation in human neural progenitor and A549 cells 18 samples shares a549
- GSE280019 Human Primary Airway Epithelium Response to HCoV-229E Infection in the Presence and Absence of Human Macrophages 16 samples shares hcov-229e
- GSE279463 Human Primary Airway Epithelium Response to HCoV-229E Infection 8 samples shares hcov-229e
- GSE306614 Effect of depletion of NEAT1 on gene expression of A549 cells during influenza virus infection. 6 samples shares a549
- GSE280627 Human Liver Epithelial Cell Chromatin Accessibility Response to HCoV-229E Infection 24 samples shares hcov-229e
- GSE210288 Effect of PFKFB3 overexpression on A549 in VSV infection. 8 samples shares a549
- GSE304966 Transcriptomic profiling of A549 cells in response to dexamethasone, in the context of light-controlled GR degradation using novel GR-PhotoPROTACs 36 samples shares a549
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.