Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 32 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 32 samples: 11 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279347_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1172125 and SRA study SRP538155. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 11 replicated groups read from 32 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8567621 GNP H3K4me3 ChIPseq replicate 1
- GSM8567622 GNP input 1 GNP input
- GSM8567623 GNP H3K4me1 ChIPseq replicate 1 GNP H3K4me1 ChIPseq
- GSM8567624 GNP H3K4me1 ChIPseq replicate 2 GNP H3K4me1 ChIPseq
- GSM8567625 GNP input 2 GNP input
- GSM8567626 GNP H3K27me3 ChIPseq replicate 1 GNP H3K27me3 ChIPseq
- GSM8567627 GNP input 3 GNP input
- GSM8567628 GNP H3K27me3 ChIPseq replicate 2 GNP H3K27me3 ChIPseq
- GSM8567629 GNP H3K27ac ChIPseq replicate 1 GNP H3K27ac ChIPseq
- GSM8567630 GNP input 4 GNP input
- GSM8567631 GNP H3K27ac ChIPseq replicate 2 GNP H3K27ac ChIPseq
- GSM8567632 GNP H3K36me3 ChIPseq replicate 1
- GSM8567633 GNP H2Aubi119 ChIPseq replicate 1 GNP H2Aubi119 ChIPseq
- GSM8567634 GNP input native
- GSM8567635 GNP H2Aubi119 ChIPseq replicate 2 GNP H2Aubi119 ChIPseq
- GSM8567636 GNP RNA pol2 Ser5-phospho replicate 1 GNP RNA pol2 Ser5-phosp…
- GSM8567637 GNP RNA pol2 Ser5-phospho replicate 2 GNP RNA pol2 Ser5-phosp…
- GSM8567638 GNP input 5 GNP input
- GSM8567639 GNP Ring1 ChIPseq replicate 1 GNP Ring1 ChIPseq
- GSM8567640 GNP Ring1 ChIPseq replicate 2 GNP Ring1 ChIPseq
- GSM8567641 GNP input 6 GNP input
- GSM8567642 GNP MIRAseq replicate 1 GNP MIRAseq
- GSM8567643 GNP MIRAseq input 1 GNP MIRAseq input
- GSM8567644 GNP MIRAseq replicate 2 GNP MIRAseq
- GSM8567645 GNP MIRAseq input 2 GNP MIRAseq input
- GSM8567646 GNP MIRAseq replicate 3 GNP MIRAseq
- GSM8567647 GNP MIRAseq input 3 GNP MIRAseq input
- GSM8567648 MB H3K27me3 replicate 1 MB H3K27me3
- GSM8567649 MB input 1 MB input
- GSM8567650 MB H3K27me3 replicate 2 MB H3K27me3
- GSM8567651 MB input 2 MB input
- GSM8588379 GNP ATACseq
- GSE297048 EZH2 alters aggressive variant prostate cancer subtype evolution, but is not required for neuroendocrine prostate cancer [ChIP-seq] 40 samples shares ezh2, chip-seq
- GSE250574 CCN6/WISP3 suppresses metaplastic breast carcinoma by antagonizing a WNT/b-catenin/EZH2 cascade [ChIP-seq] 16 samples shares ezh2, chip-seq
- GSE293592 Maternal immune activation delays DNA methylation and physiological maturation of cortical excitatory neurons 106 samples shares activation, delays
- GSE297574 H3K9 di-methylation dynamics underlies mouse minor zygotic genome activation [spike-in ChIP-seq of mESC] 64 samples shares activation, chip-seq
- GSE245647 The Heme-regulated transcriptional repressor, BACH1 safeguards macrophage enhancer selection, activation andtissue adaptation [ChIP-seq] 62 samples shares activation, chip-seq
- GSE196745 Changes in Ikaros binding and histone-modifications upon oncogenic β-catenin activation [ChIP-Seq] 30 samples shares activation, chip-seq
- GSE266022 Nrf2-mediated chromatin activation of hyperosmotic response genes attenuates heat-induced renal injury [ChIP-seq] 24 samples shares activation, chip-seq
- GSE263359 Chromatin Modification Abnormalities by CHD7 and KMT2C Loss Promote Medulloblastoma Progression [ATAC-seq] 11 samples shares medulloblastoma, normal
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.