Function of PLAGL1 during osteogenesis of condyle
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × condy-Cre-0d vs 3 × condy-cre-4d vs 3 × condy-nc-0d vs 3 × condy-nc-4dGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PLAGL1-IGF2 axis regulates osteogenesis of postnatal condyle developmentInternational journal of oral science · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279365_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1172301 and SRA study SRP538243. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8568031 condy-Cre-0d-1 condy-Cre-0d
- GSM8568032 condy-Cre-0d-2 condy-Cre-0d
- GSM8568033 condy-Cre-0d-3 condy-Cre-0d
- GSM8568034 condy-cre-4d-1 condy-cre-4d
- GSM8568035 condy-cre-4d-2 condy-cre-4d
- GSM8568036 condy-cre-4d-3 condy-cre-4d
- GSM8568037 condy-nc-0d-1 condy-nc-0d
- GSM8568038 condy-nc-0d-2 condy-nc-0d
- GSM8568039 condy-nc-0d-3 condy-nc-0d
- GSM8568040 condy-nc-4d-1 condy-nc-4d
- GSM8568041 condy-nc-4d-2 condy-nc-4d
- GSM8568042 condy-nc-4d-3 condy-nc-4d
- GSE279367 Function of PLAGL1 during osteogenesis of mandible [RNA-seq] 9 samples shares plagl1, osteogenesis
- GSE298229 The PLAGL1-KLF4-IRX5 axis promotes the osteogenesis of periosteal progenitors during mandible regeneration [CUT＆tag-Seq] 9 samples shares plagl1, osteogenesis
- GSE298228 The PLAGL1-KLF4-IRX5 axis promotes the osteogenesis of periosteal progenitors during mandible regeneration [ATAC-seq] 4 samples shares plagl1, osteogenesis
- GSE299947 Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503 [RNA-seq] 42 samples shares plagl1
- GSE299946 Plagl1 and Lrrc58 control mammalian body size by triggering target-directed microRNA degradation of miR-322 and miR-503 [AGO-CLASH] 20 samples shares plagl1
- GSE228191 Gene expression profile at single cell level of Wild type and Plagl1 knock out retina at P7 4 samples shares plagl1
- GSE333701 Transcriptional Profiling of Otic Capsule and Femur in the oim Mouse Model of Osteogenesis Imperfecta 140 samples shares osteogenesis
- GSE236921 Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition 46 samples shares osteogenesis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.