IL-18 engineered to avoid decoy-receptor binding enhances tumor rejection by anti-CTLA-4 in kidney cancer models through immune microenvironment remodeling.

Direct links to NCBI, no account and no request form: the whole study as GSE279662_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1171556 and SRA study SRP537847. Searching any of these in the dataset finder brings you back here.

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• GSE270050 Expansion of Tumor-Infiltrating CD8+ T Cell Clonotypes Occurs in the Spleen in Response to Immune Checkpoint Blockade 29 samples
• GSE234186 Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity 26 samples
• GSE327213 Increased mRNA translation delays tumor initiation and exposes a therapeutic vulnerability in lung cancer 16 samples
• GSE304864 Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq. 11 samples
• GSE314584 Toll-Like-Receptor 5 Reduces Lung Dysbiosis and Protects Against Pulmonary Fibrosis 124 samples
• GSE250056 Targeting chemokine crosstalk between T-cells and macrophages to treat immune checkpoint inhibito-mediated myocarditis 68 samples
• GSE314859 The degradation of maternal RNA-binding protein 4E-T regulates translational activation to ensure maternal-to-zygotic transition in mouse embryos 67 samples
• GSE269045 Inflammatory immune modulators of AML lung infiltration and respiratory failure 56 samples

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