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FUT8 is a critical driver of prostate tumour growth and can be targeted using fucosylation inhibitors

GSE280132 Homo sapiens Expression profiling by high throughput sequencing 12 samples 2025/05/19 GPL21697GPL24676
Summary
To identify signalling pathways altered by FUT8 in prostate cancer cells, we established luciferase-tagged CWR22Rv1 stable cell lines in which FUT8 was overexpressed (OE) and luciferase-tagged PC3 cell lines in which FUT8 was knocked down (KD). We then performed differential gene expression, Gene Ontology and GSEA analyses using data obtained from RNA-seq of the control and FUT8 overexpression, and the control and knockdown cell lines.
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NCBI GEO page ↗ Paper (PMID 40387385) ↗ {# Names what the click gives you. "Open in finder" meant nothing to a visitor who arrived from a search engine and has never seen the tool. #} Find more human RNA-seq datasets →
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