GEO series
SOAT1 knockout enhances sensitivity of liver cancer cells to T cell-based immunotherapy [RNA-seq]
GSE280148
Homo sapiens; Mus musculus
Expression profiling by high throughput sequencing
24 samples
2025/12/31
GPL24676GPL24247
Summary
SOAT1 knockout enhances the responsiveness of human liver cancers to T cell-based therapies without significantly impacting tumor proliferation. We aimed to elucidate how SOAT1 knockout influences sensitivity to T cell therapy. We performed bulk RNA-seq analysis on SOAT1-KO and vector-transduced Hepa1-6 cells and Huh7 cells.
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