In vitro arrayed OVOL2 overexpression in PDA Cell Lines (bulk RNA-Seq)
RNA-seq (gene expression) · human · 51 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 51 samples: 17 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE280160_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1176580 and SRA study SRP540876. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 51 samples.
How we read this: 17 replicated groups read from 51 sample titles; they account for 51 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8589059 HPAFII NORMAL 1 HPAFII NORMAL
- GSM8589060 PATU8988S NORMAL 3 PATU8988S NORMAL
- GSM8589061 KP4 mCHERRY M2RTTA 2 KP4 mCHERRY M2RTTA
- GSM8589062 PANC1 NORMAL 1 PANC1 NORMAL
- GSM8589063 PANC1 mCHERRY + M2RTTA 3 PANC1 mCHERRY + M2RTTA
- GSM8589064 PK45H mCHERRY 2 PK45H mCHERRY
- GSM8589065 PK45H OVOL2 + M2RTTA 1 PK45H OVOL2 + M2RTTA
- GSM8589066 HPAFII NORMAL 2 HPAFII NORMAL
- GSM8589067 PK45H NORMAL 1 PK45H NORMAL
- GSM8589068 KP4 mCHERRY M2RTTA 3 KP4 mCHERRY M2RTTA
- GSM8589069 PANC1 NORMAL 2 PANC1 NORMAL
- GSM8589070 PANC1 OVOL2 1 PANC1 OVOL2
- GSM8589071 PK45H mCHERRY 3 PK45H mCHERRY
- GSM8589072 PK45H OVOL2 + M2RTTA 2 PK45H OVOL2 + M2RTTA
- GSM8589073 HPAFII NORMAL 3 HPAFII NORMAL
- GSM8589074 PK45H NORMAL 2 PK45H NORMAL
- GSM8589075 KP4 OVOL2 1 KP4 OVOL2
- GSM8589076 PANC1 NORMAL 3 PANC1 NORMAL
- GSM8589077 PANC1 OVOL2 2 PANC1 OVOL2
- GSM8589078 PK45H mCHERRY + M2RTTA 1 PK45H mCHERRY + M2RTTA
- GSM8589079 PK45H OVOL2 + M2RTTA 3 PK45H OVOL2 + M2RTTA
- GSM8589080 KP4 NORMAL 1 KP4 NORMAL
- GSM8589081 PK45H NORMAL 3 PK45H NORMAL
- GSM8589082 KP4 OVOL2 2 KP4 OVOL2
- GSM8589084 PANC1 mCHERRY 1 PANC1 mCHERRY
- GSM8589085 PANC1 OVOL2 3 PANC1 OVOL2
- GSM8589086 PK45H mCHERRY + M2RTTA 2 PK45H mCHERRY + M2RTTA
- GSM8589088 KP4 NORMAL 2 KP4 NORMAL
- GSM8589090 KP4 mCHERRY 1 KP4 mCHERRY
- GSM8589091 KP4 OVOL2 3 KP4 OVOL2
- GSM8589093 PANC1 mCHERRY 2 PANC1 mCHERRY
- GSM8589094 PANC1 OVOL2 + M2RTTA 1 PANC1 OVOL2 + M2RTTA
- GSM8589096 PK45H mCHERRY + M2RTTA 3 PK45H mCHERRY + M2RTTA
- GSM8589097 KP4 NORMAL 3 KP4 NORMAL
- GSM8589099 KP4 mCHERRY 2 KP4 mCHERRY
- GSM8589100 KP4 OVOL2 M2RTTA 1 KP4 OVOL2 M2RTTA
- GSM8589102 PANC1 mCHERRY 3 PANC1 mCHERRY
- GSM8589103 PANC1 OVOL2 + M2RTTA 2 PANC1 OVOL2 + M2RTTA
- GSM8589105 PK45H OVOL2 1 PK45H OVOL2
- GSM8589106 PATU8988S NORMAL 1 PATU8988S NORMAL
+ 11 more — browse all 51 samples with per-sample file links →
- GSE161368 TF overexpression assay in PDA cell lines (Bulk RNA-Seq) 69 samples shares pda, overexpression, rna-seq, lines, bulk
- GSE205154 Bulk RNA-Seq gene expression data for 289 primary and metastatic pancreatic ductal adenocarcinoma (PDAC) tumor samples from FFPE blocks. 289 samples shares pda, rna-seq, bulk
- GSE252002 In vitro drug screening of RAF/MEK/ERK Inhibitors in two PDA Cell Lines 152 samples shares pda, vitro, lines
- GSE275078 In vitro drug screening of RAF/MEK/ERK Inhibitors in combination with Autophagy inhibition in the context of two PDA Cell Lines 136 samples shares pda, vitro, lines
- GSE281525 RNA-sequence data of clinically never-metastatic primary small cell lung cancer cases and small cell lung cancer metastasis cases, FOXA2 knock-down and overexpression in cell lines 61 samples shares overexpression, rna-seq, lines
- GSE256290 Bulk RNA-seq after Overexpression of EFNB2 in U266 Multiple Myeloma Cells 10 samples shares overexpression, rna-seq, bulk
- GSE295349 KLF5 interacts with RUVBL1/2 to activate classical and basal lineage identities in PDAC [RNA-seq] 183 samples shares pda, rna-seq
- GSE298803 ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC [CRISPRi RNA-seq] 70 samples shares pda, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.