GEO series
CD4T in breast cancer
GSE280205
Homo sapiens
Expression profiling by high throughput sequencing
18 samples
2024/11/02
GPL24676
Summary
We found that a distinctive subset of IL-1+ CXCL3+ CD4 (Fer-CD4) T lymphocytes that were enriched in chemoresistant tumors and revealed the immune-reshaping capacity of neutrophil ferroptosis and its reciprocal feedback regulation with Fer-CD4 T cells, identifying promising targets for restoring anticancer immunosurveillance and reversing chemoresistance.
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