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Genome-wide mapping of human SMYD3 and H3K4me3 in the HN-6 (control) and 5-3 (SMYD3 KO) HPV-negative head and neck squamous cell carcinoma cell line.

GSE280252 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 9 samples Submitted 2024/11/01 Platform GPL30173
Summary
We used CUT&RUN to evaluate the genome-wide mapping of human SMYD3 and H3K4me3 in HN-6 and 5-3 (SMYD3 KO) cells.
Published in
SMYD3 drives cell cycle and epithelial-mesenchymal transition pathways through dual gene transcriptional repression and activation in HPV-negative head and neck cancer
Murali M, Saeed A, Kim S et al. · Scientific reports 2025 · PMID 39762343 · doi:10.1038/s41598-024-83396-2
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Direct links to NCBI, no account and no request form: the whole study as GSE280252_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1177444 and SRA study SRP540663. Searching any of these in the dataset finder brings you back here.

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