GEO series
RNA sequencing of non-targetting ASOs on HEK293 and U2OS cells
GSE280432
Homo sapiens
Expression profiling by high throughput sequencing
36 samples
2025/05/19
GPL24676
Summary
Non-targetting ASOs are commonly used as negative controls in vitro and in vivo. Here, we compare the transcriptomic profile of HEK293 and U2OS, following 3 days treatment with 3 different non-targetting ASOs. In those conditions, we did not find major transcriptomic changes following ASO treatment, confirming that they are appropriate negative controls.
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Paper (PMID 40588516) ↗
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