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Effect of MSMP inhibition on the gene expression profiles of rheumatoid fibroblast-like synoviocytes

GSE280445 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2024/10/28 Platform GPL24676
Summary
To explore the downstream target of MSMP, RNA-sequencing (RNA-seq) was used to display gene expression profiles in fibroblast-like synoviocytes (FLSs) from 3 patients with rheumatoid arthritis (RA) between control siRNA (siC) group and siMSMP-2 group (with the highest interference efficiency for MSMP). The heatmap and volcano diagram showed a total of 216 differentially expressed genes with 77 upregulated genes and 139 downregulated genes (Fold change≥1.5,p<0.05)
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Also filed as BioProject PRJNA1178612 and SRA study SRP541552. Searching any of these in the dataset finder brings you back here.

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