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Expression profiling of circular RNAs in cells from human carotid plaque biopsies by single-cell RNA sequencing

GSE280608 Homo sapiens Expression profiling by high throughput sequencing; Third-party reanalysis Submitted 2025/04/01
Summary
To identify the origin of circular RNAs (circRNAs) in human atherosclerotic plaques, we analyzed the expression levels of circRNAs identified during the differentiation of human pluripotent stem cells (hiPSCs) into vascular endothelial cells (ECs) and smooth muscle cells (SMCs) in carotid biopsies by single-cell RNA sequencing.
Published in
Circular RNAs increase during vascular cell differentiation and are biomarkers for vascular disease
Northoff BH, Herbst A, Wenk C et al. · Cardiovascular research 2025 · PMID 39901821 · doi:10.1093/cvr/cvaf013
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