PAR3-mediated coordination of hepatocyte proliferation, maturation, and architecture in liver development and regeneration
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 128 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 128 samples: 115 distinct titles, 9 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PAR3-mediated coordination of hepatocyte proliferation, maturation, and architecture in liver development and regenerationNature communications · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE281035_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1181868 and SRA study SRP543079. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 128 sample titles: 115 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8609581 E17.5 Foxa3Cre Pard3WT rep1
- GSM8609582 E17.5 Foxa3Cre Pard3WT rep2
- GSM8609583 E17.5 Foxa3Cre Pard3WT rep3
- GSM8609584 E17.5 Foxa3Cre Pard3HMKO rep1
- GSM8609585 E17.5 Foxa3Cre Pard3HMKO rep2
- GSM8609586 E17.5 Foxa3Cre Pard3HMKO rep3
- GSM8609587 E17.5 Foxa3Cre YapWT rep1
- GSM8609588 E17.5 Foxa3Cre YapWT rep2
- GSM8609589 E17.5 Foxa3Cre YapWT rep3
- GSM8609590 E17.5 Foxa3Cre YapHMKO rep1
- GSM8609591 E17.5 Foxa3Cre YapHMKO rep2
- GSM8609592 E17.5 Foxa3Cre YapHMKO rep3
- GSM8609593 E15.5 culture 2d Foxa3Cre Pard3WT control rep1
- GSM8609594 E15.5 culture 2d Foxa3Cre Pard3WT control rep2
- GSM8609595 E15.5 culture 2d Foxa3Cre Pard3WT PD rep1
- GSM8609596 E15.5 culture 2d Foxa3Cre Pard3WT PD rep2
- GSM8609597 E15.5 culture 2d Foxa3Cre Pard3WT TPPB rep1
- GSM8609598 E15.5 culture 2d Foxa3Cre Pard3WT TPPB rep2
- GSM8609599 E15.5 culture 2d Foxa3Cre Pard3HMKO control rep1
- GSM8609600 E15.5 culture 2d Foxa3Cre Pard3HMKO control rep2
- GSM8609601 E15.5 culture 2d Foxa3Cre Pard3HMKO PD rep1
- GSM8609602 E15.5 culture 2d Foxa3Cre Pard3HMKO PD rep2
- GSM8633127 E13.5 B6C3F1 WT rep1 1-21
- GSM8633128 E13.5 B6C3F1 WT rep2 1-25
- GSM8633129 E14.5 B6C3F1 WT rep1 1-45
- GSM8633130 E14.5 B6C3F1 WT rep2 1-39
- GSM8633131 E15.5 B6C3F1 WT rep1 1-39
- GSM8633132 E15.5 B6C3F1 WT rep2 1-43
- GSM8633133 E15.5 B6C3F1 WT rep3 1-42
- GSM8633134 E16.5 B6C3F1 WT rep1 1-42
- GSM8633135 E16.5 B6C3F1 WT rep2 1-42
- GSM8633136 E16.5 B6C3F1 WT rep3 1-34
- GSM8633137 E17.5 B6C3F1 WT rep1 1-128
- GSM8633138 E17.5 B6C3F1 WT rep2 1-133
- GSM8633141 E15.5 Foxa3Cre Pard3WT rep1 1-41
- GSM8633142 E15.5 Foxa3Cre Pard3WT rep2 1-42
- GSM8633143 E15.5 Foxa3Cre Pard3HMKO rep1 1-42
- GSM8633144 E15.5 Foxa3Cre Pard3HMKO rep2 1-44
- GSM8633145 E15.5 Foxa3Cre YapWT rep1 1-40
- GSM8633146 E15.5 Foxa3Cre YapWT rep2 1-26
+ 88 more — browse all 128 samples with per-sample file links →
- GSE273213 An Nrf2-NF-kB cross-talk controls hepatocyte proliferation in the normal and injured liver 10 samples shares proliferation, hepatocyte, liver
- GSE302604 Chronic intermittent hypoxia mimicking sleep apnea reshapes the liver circadian metabolic architecture 36 samples shares architecture, liver
- GSE274973 Mouse liver assembloids model periportal architecture and biliary fibrosis [scRNA-seq] 13 samples shares architecture, liver
- GSE276126 STAT1 regulates immune-mediated intestinal stem cell proliferation and epithelial regeneration 13 samples shares proliferation, regeneration
- GSE306766 Kdm6b-mediated epigenetic coordination of temporal precision during motor neuron differentiation 47 samples shares coordination
- GSE220043 Arresting the Bad Seed: HDAC3 Regulates Proliferation of Different Microglia after Ischemic Stroke 22 samples shares proliferation
- GSE248653 Nicotinamide mononucleotide promotes female germline stem cell proliferation by activating the H4K16ac-Hmgb1-Fyn-PLD signaling pathway through epigenetic remodeling 20 samples shares proliferation
- GSE206011 Stepwise de novo establishment of inactive X chromosome architecture in early development 262 samples shares architecture
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.