Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma [RNA-Seq, 2]
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 6 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastomaCell reports · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE281093_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1182254 and SRA study SRP543288. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 6 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8610755 Kelly_shRCOR1_NT_rep1 Kelly_shRCOR1_NT
- GSM8610756 Kelly_shRCOR1_NT_rep2 Kelly_shRCOR1_NT
- GSM8610757 Kelly_shRCOR1_72h_rep1 Kelly_shRCOR1_72h
- GSM8610758 Kelly_shRCOR1_72h_rep2 Kelly_shRCOR1_72h
- GSM8610759 Kelly_shRCOR2_NT_rep1 Kelly_shRCOR2_NT
- GSM8610760 Kelly_shRCOR2_NT_rep2 Kelly_shRCOR2_NT
- GSM8610761 Kelly_shRCOR2_72h_rep1 Kelly_shRCOR2_72h
- GSM8610762 Kelly_shRCOR2_72h_rep2 Kelly_shRCOR2_72h
- GSM8610763 Kelly_shCTRL_NT_rep1 Kelly_shCTRL_NT
- GSM8610764 Kelly_shCTRL_NT_rep2 Kelly_shCTRL_NT
- GSM8610765 Kelly_shCTRL_72h_rep1 Kelly_shCTRL_72h
- GSM8610766 Kelly_shCTRL_72h_rep2 Kelly_shCTRL_72h
- GSE348445 Identification and Characterization of Adrenergic and Mesenchymal Cancer Cell States in Neuroblastoma Using Spatial-Omics [RNA-Seq] 33 samples shares neuroblastoma, adrenergic, rna-seq
- GSE49711 RNA-Seq reveals an unprecedented complexity of the neuroblastoma transcriptome and is suitable for clinical endpoint prediction [RNA-Seq] 498 samples shares neuroblastoma, rna-seq
- GSE245175 Neuroblastoma heterogeneity and plasticity over disease progression are rooted in the dynamics of an early sympathetic transcriptional trajectory 79 samples shares transcription, neuroblastoma
- GSE269826 Conserved patterns of transcriptional dysregulation, heterogeneity and cell states in clear cell kidney cancer [scRNA-seq] 79 samples shares transcription, rna-seq
- GSE189357 Spatiotemporal transcriptional atlas of lung adenocarcinoma from adenocarcinoma in situ to invasive carcinoma [scRNA-seq] 9 samples shares transcription, rna-seq
- GSE273326 A trimeric USP11-USP7-TCEAL1 complex stabilizes paused RNAPII to sustain oncogenic transcription 63 samples shares transcription, sustain
- GSE318861 Quantitative analysis of Tat-dependent and host-driven HIV transcription by ChIP-seq and RNA-seq 52 samples shares transcription, rna-seq
- GSE332618 Identification and Characterization of Adrenergic and Mesenchymal Cancer Cell States in Neuroblastoma Using Spatial-Omics [Spatial Transcriptomics] 16 samples shares neuroblastoma, adrenergic
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.