Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates gene expression in mice after a mild chronic stress paradigm
RNA-seq (gene expression) · mouse · 80 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 80 samples: 80 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates depression-like behaviour in female mice after a mild chronic stress paradigmTranslational psychiatry · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE281404_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1183804. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 80 sample titles: 80 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8619943 Hippocampus, KO, f, CS, 2277, biol rep 1
- GSM8619944 Hippocampus, KO, f, CS, 2317, biol rep 2
- GSM8619945 Hippocampus, KO, f, CS, 2399, biol rep 3
- GSM8619946 Hippocampus, KO, f, CS, 2284, biol rep 4
- GSM8619947 Hippocampus, KO, f, CS, 2407, biol rep 5
- GSM8619948 Hippocampus, KO, f, CS, 2416, biol rep 6
- GSM8619949 Hippocampus, KO, f, K, 2252, biol rep 1
- GSM8619950 Hippocampus, KO, f, K, 2336, biol rep 2
- GSM8619951 Hippocampus, KO, f, K, 2343, biol rep 3
- GSM8619952 Hippocampus, KO, f, K, 2273, biol rep 4
- GSM8619953 Hippocampus, KO, f, K, 2406, biol rep 5
- GSM8619954 Hippocampus, KO, f, K, 2430, biol rep 6
- GSM8619955 Hippocampus, KO, m, CS, 2269, biol rep 1
- GSM8619956 Hippocampus, KO, m, CS, 2256, biol rep 2
- GSM8619957 Hippocampus, KO, m, CS, 2433, biol rep 3
- GSM8619958 Hippocampus, KO, m, CS, 2393, biol rep 4
- GSM8619959 Hippocampus, KO, m, K, 2246, biol rep 1
- GSM8619960 Hippocampus, KO, m, K, 2303, biol rep 2
- GSM8619961 Hippocampus, KO, m, K, 2412, biol rep 3
- GSM8619962 Hippocampus, KO, m, K, 2341, biol rep 4
- GSM8619963 Hippocampus, WT, f, CS, 2274, biol rep 1
- GSM8619964 Hippocampus, WT, f, CS, 2409, biol rep 2
- GSM8619965 Hippocampus, WT, f, CS, 2285, biol rep 3
- GSM8619966 Hippocampus, WT, f, CS, 2315, biol rep 4
- GSM8619967 Hippocampus, WT, f, CS, 2397, biol rep 5
- GSM8619968 Hippocampus, WT, f, CS, 2417, biol rep 6
- GSM8619969 Hippocampus, WT, f, K, 2278, biol rep 1
- GSM8619970 Hippocampus, WT, f, K, 2253, biol rep 2
- GSM8619971 Hippocampus, WT, f, K, 2408, biol rep 3
- GSM8619972 Hippocampus, WT, f, K, 2337, biol rep 4
- GSM8619973 Hippocampus, WT, f, K, 2342, biol rep 5
- GSM8619974 Hippocampus, WT, f, K, 2429, biol rep 6
- GSM8619975 Hippocampus, WT, m, CS, 2271, biol rep 1
- GSM8619976 Hippocampus, WT, m, CS, 2257, biol rep 2
- GSM8619977 Hippocampus, WT, m, CS, 2434, biol rep 3
- GSM8619978 Hippocampus, WT, m, CS, 2395, biol rep 4
- GSM8619979 Hippocampus, WT, m, K, 2244, biol rep 1
- GSM8619980 Hippocampus, WT, m, K, 2302, biol rep 2
- GSM8619981 Hippocampus, WT, m, K, 2339, biol rep 3
- GSM8619982 Hippocampus, WT, m, K, 2411, biol rep 4
+ 40 more — browse all 80 samples with per-sample file links →
- GSE254687 PARK7/DJ-1 deficiency modulates microglial activation in response to LPS-induced inflammation 19 samples shares deficiency, modulates
- GSE305462 Rac1 palmitoylation is required for cardiac stress adaptation and regulation of Protein Kinase A signaling 18 samples shares palmitoyl, stress
- GSE284360 Co-deficiency of the BLM and RECQL1 Helicases Causes Synthetic Lethality, Pronounced Replication Stress, and Loss of Chromatid Cohesion 12 samples shares deficiency, stress
- GSE241850 Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer progression via extracellular vesicle transfer of m6A-modified RNAs 57 samples shares deficiency, stress
- GSE243060 Multi-organ Transcriptome Atlas of a Mouse Model of Relative Energy Deficiency in Sport (REDs) 419 samples shares deficiency
- GSE254229 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice 141 samples shares deficiency
- GSE267786 Impact of SLC15A4, TASL and TASL2(Gm6377) deficiency on endolysosomal TLR7 and TLR9 responses 95 samples shares deficiency
- GSE260623 Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma [bulkRNA] 91 samples shares deficiency
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.