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CALIPERS: Cell cycle-aware live imaging for phenotyping experiments and regeneration studies

GSE281528 Homo sapiens Expression profiling by high throughput sequencing; Other 3 samples Submitted 2026/06/25 Platform GPL30882
Summary
We introduce CALIPERS, a Fluorescence Ubiquitin Cell Cycle Indicator enabling cell cycle-aware phenotyping based on multiplexed live-cell imaging. We validate CALIPERS in three- and four-color reporter lines (HaCaT) and human induced pluripotent stem cells (WTC-11), co-expressing genetically encoded structural and functional fluorescent sensors. To exemplify the broad applications of CALIPERS, we show cell cycle-aware phenotyping in live-cell imaging applications ranging from proliferation and migration to cardiac-specific maturation and drug testing.
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Also filed as BioProject PRJNA1184339 and SRA study SRP544326. Searching any of these in the dataset finder brings you back here.

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