Gastric Bypass Elicits Persistent Gut Adaptation and Unique Diabetes Remission-Related Metabolic Gene Regulation
RNA-seq (gene expression) · human · 56 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 56 samples: 56 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Gastric bypass elicits persistent gut adaptation and unique diabetes remission-related metabolic gene regulationObesity (Silver Spring, Md.) · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE281598_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1184774 and SRA study SRP544721. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 56 sample titles: 56 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8624482 P_01_C
- GSM8624483 P_02_C
- GSM8624484 P_03_C
- GSM8624485 P_04_C
- GSM8624486 P_08_D
- GSM8624487 P_09_C
- GSM8624488 P_10_D
- GSM8624489 P_11_D
- GSM8624490 P_13_C
- GSM8624491 P_15_C
- GSM8624492 P_16_C
- GSM8624493 P_18_C
- GSM8624494 P_19_D
- GSM8624495 P_20_D
- GSM8624496 P_21_D
- GSM8624497 P_23_D
- GSM8624498 P_25_D
- GSM8624499 P_27_C
- GSM8624500 P_28_D
- GSM8624501 P_29_C
- GSM8624502 P_30_C
- GSM8624503 P_31_C
- GSM8624504 P_32_D
- GSM8624505 P_33_D
- GSM8624506 P_34_D
- GSM8624507 P_35_D
- GSM8624508 P_36_D
- GSM8624509 P_37_D
- GSM8624510 B_01_C
- GSM8624511 B_02_C
- GSM8624512 B_03_C
- GSM8624513 B_04_C
- GSM8624514 B_08_D
- GSM8624515 B_09_C
- GSM8624516 B_10_D
- GSM8624517 B_11_D
- GSM8624518 B_13_C
- GSM8624519 B_15_C
- GSM8624520 B_16_C
- GSM8624521 B_18_C
+ 16 more — browse all 56 samples with per-sample file links →
- GSE341455 Skeletal muscle reprogramming of metabolic, ribosomal and developmental pathways contributes to Roux-en-Y gastric bypass-induced adaptation in women 70 samples shares adaptation, gastric, bypass
- GSE296615 Glycation DNA immunoprecipitation sequencing (GlyDIP-seq) for detecting epigenetic effects unique to diabetes 10 samples shares diabetes, unique
- GSE320155 scRNA‑seq of human intra‑hepatic CD4⁺ T cells reveals unique Treg transcriptional identities and two steady‑state tissue‑adaptation programs across healthy and HCC liver samples 60 samples shares adaptation, unique
- GSE86469 Single cell transcriptomics defines human islet cell signatures and reveals cell-type-specific expression changes in type 2 diabetes [single cell] 638 samples shares diabetes
- GSE314188 Responders to low-dose ATG induce CD4+ T cell exhaustion in type 1 diabetes 514 samples shares diabetes
- GSE280267 Glycine Receptor Activity in β Cells Is Downregulated in Type 2 Diabetes and After High Glucose Culture 199 samples shares diabetes
- GSE311827 AP-1 Mediates Cellular Adaptation and Memory Formation [Bulk RNA-seq] 192 samples shares adaptation
- GSE234181 Long-term multi-modal recording reveals epigenetic adaptation routes in dormant breast cancer cells [scRNA-Seq] 184 samples shares adaptation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.