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Transcriptomic analysis of GRHL2 regulated genes in HepG2 cells

GSE281713 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/12/30 Platform GPL28038
Summary
HepG2 cells were transfected with a plasmid coding for GRHL2 fused to a flag tag or a pcDNA vector and RNA were processed for RNAseq
Published in
Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation
Vasseur L, Gheeraert C, Dubois-Chevalier J et al. · PLoS biology 2025 · PMID 41385584 · doi:10.1371/journal.pbio.3003547
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Direct links to NCBI, no account and no request form: the whole study as GSE281713_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1185273 and SRA study SRP544753. Searching any of these in the dataset finder brings you back here.

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