Gene expression profile at sorted microglia and border-associated macrophage with Ms4a3-Cre: R26-TdTomato: Cx3cr1-gfp bone marrow transplantation
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 5 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging miceCell reports · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE282221_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1187607 and SRA study SRP545997. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 5 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8639523 DR_BMT_host_Microglia_1 DR_BMT_host_Microglia
- GSM8639524 DR_BMT_host_Microglia_2 DR_BMT_host_Microglia
- GSM8639525 DR_BMT_host_Microglia_3 DR_BMT_host_Microglia
- GSM8639526 DR_BMT_host_Microglia_4 DR_BMT_host_Microglia
- GSM8639527 DR_BMT_moMicroglia_1 DR_BMT_moMicroglia
- GSM8639528 DR_BMT_moMicroglia_2 DR_BMT_moMicroglia
- GSM8639529 DR_BMT_moMicroglia_3 DR_BMT_moMicroglia
- GSM8639530 DR_BMT_moMicroglia_4 DR_BMT_moMicroglia
- GSM8639531 DR_BMT_HSC_Microglia_1 DR_BMT_HSC_Microglia
- GSM8639532 DR_BMT_HSC_Microglia_2 DR_BMT_HSC_Microglia
- GSM8639533 DR_BMT_HSC_Microglia_3 DR_BMT_HSC_Microglia
- GSM8639534 DR_BMT_HSC_Microglia_4 DR_BMT_HSC_Microglia
- GSM8639535 DR_BMT_moBAM_1 DR_BMT_moBAM
- GSM8639536 DR_BMT_moBAM_2 DR_BMT_moBAM
- GSM8639537 DR_BMT_moBAM_3 DR_BMT_moBAM
- GSM8639538 DR_BMT_moBAM_4 DR_BMT_moBAM
- GSM8639539 DR_BMT_HSC_BAM_1 DR_BMT_HSC_BAM
- GSM8639540 DR_BMT_HSC_BAM_2 DR_BMT_HSC_BAM
- GSE267137 Gene expression profile of sorted microglia and CD206 border-associated macrophages obtained from mice 16 samples shares border-associated, macrophage, microglia, sorted
- GSE282946 Gene expression profile at single cell level of YS-derived cells and monocyte-derived cells from brain parenchyma and leptomeninges of Ms4a3-Cre: R26-TdTomato: Cx3cr1-gfp mice 1 samples shares cx3cr1-gfp, ms4a3-cre, r26-tdtomato
- GSE282223 Gene expression profile of microglia and border-associated macrophages carrying hDNMT3A mutation 28 samples shares border-associated, macrophage, microglia
- GSE277981 RNA sequencing data of dural macrophages isolated from brains of Cx3cr1-GFP mice at different ages. 15 samples shares cx3cr1-gfp, macrophage
- GSE262851 Hypoxia Inducible Factor 2α promotes tolerogenic macrophage development during cardiac transplantation through transcriptional regulation of colony stimulating factor 1 receptor 2 samples shares transplantation, macrophage
- GSE239774 CD40 induces PIR-A+ macrophages to promote chronic rejection of cardiac transplantation 2 samples shares transplantation, macrophage
- GSE239816 CD40 induces PIR-A+ macrophages to promote chronic rejection of cardiac transplantation [ChIP-seq] 4 samples shares transplantation, macrophage
- GSE165881 Establishment of hematopoietic stem cell compartment after single cell transplantation tracked by FIT approach 62 samples shares transplantation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.