Regulation of epigenetics and chromosome structure by human ORC2
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 112 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 112 samples: 104 distinct titles, 8 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Regulation of epigenetics and chromosome structure by human ORC2Cell reports · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE282340_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1188157 and SRA study SRP546234. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 112 sample titles: 104 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8641572 HCT116 p53-/- WT IgG rep 1 [CUT&RUN]
- GSM8641573 HCT116 p53-/- WT IgG rep 2 [CUT&RUN]
- GSM8641574 HCT116 p53-/- WT CTCF rep 1 [CUT&RUN]
- GSM8641575 HCT116 p53-/- WT CTCF rep 2 [CUT&RUN]
- GSM8641576 HCT116 p53-/- ORC2 deletion IgG rep 1 [CUT&RUN]
- GSM8641577 HCT116 p53-/- ORC2 deletion IgG rep 2 [CUT&RUN]
- GSM8641578 HCT116 p53-/- ORC2 deletion CTCF rep 1 [CUT&RUN]
- GSM8641579 HCT116 p53-/- ORC2 deletion CTCF rep 2 [CUT&RUN]
- GSM8641580 HCT116 p53-/- ORC2 rescue IgG rep 2 [CUT&RUN]
- GSM8641581 HCT116 p53-/- ORC2 rescue CTCF rep 1 [CUT&RUN]
- GSM8641582 HCT116 p53-/- ORC2 rescue CTCF rep 2 [CUT&RUN]
- GSM8641650 HCT116 p53-/- WT [HiC]
- GSM8641651 HCT116 p53-/- ORC2 deletion [HiC]
- GSM8641652 HCT116 p53-/- ORC2 rescue [HiC]
- GSM8643663 MN-FusionRed 0min Rep1 [ChECseq]
- GSM8643664 MN-FusionRed 0min Rep2 [ChECseq]
- GSM8643665 MN-FusionRed 0min Rep3 [ChECseq]
- GSM8643666 MN-FusionRed 10min Rep1 [ChECseq]
- GSM8643667 MN-FusionRed 10min Rep2 [ChECseq]
- GSM8643668 MN-FusionRed 10min Rep3 [ChECseq]
- GSM8643669 MN-ORC2 clone3 0min Rep1 [ChECseq]
- GSM8643670 MN-ORC2 clone3 0min Rep2 [ChECseq]
- GSM8643671 MN-ORC2 clone3 0min Rep3 [ChECseq]
- GSM8643672 MN-ORC2 clone3 10min Rep1 [ChECseq]
- GSM8643673 MN-ORC2 clone3 10min Rep2 [ChECseq]
- GSM8643674 MN-ORC2 clone3 10min Rep3 [ChECseq]
- GSM8643675 MN-ORC2 clone4 0min Rep1 [ChECseq]
- GSM8643676 MN-ORC2 clone4 0min Rep2 [ChECseq]
- GSM8643677 MN-ORC2 clone4 0min Rep3 [ChECseq]
- GSM8643678 MN-ORC2 clone4 10min Rep1 [ChECseq]
- GSM8643679 MN-ORC2 clone4 10min Rep2 [ChECseq]
- GSM8643680 MN-ORC2 clone4 10min Rep3 [ChECseq]
- GSM8646364 MN-FusionRed 0min Rep1 [ORC1 ChECseq]
- GSM8646365 MN-FusionRed 0min Rep2 [ORC1 ChECseq]
- GSM8646366 MN-FusionRed 0min Rep3 [ORC1 ChECseq]
- GSM8646367 MN-FusionRed 10min Rep1 [ORC1 ChECseq]
- GSM8646368 MN-FusionRed 10min Rep2 [ORC1 ChECseq]
- GSM8646369 MN-FusionRed 10min Rep3 [ORC1 ChECseq]
- GSM8646370 MN-ORC1 clone3 0min Rep1 [ORC1 ChECseq]
- GSM8646371 MN-ORC1 clone3 0min Rep2 [ORC1 ChECseq]
+ 72 more — browse all 112 samples with per-sample file links →
- GSE282458 Regulation of epigenetics and chromosome structure by human ORC2 [ORC2 ChECseq] 18 samples shares orc2, epigenetics, chromosome, structure
- GSE282576 Regulation of epigenetics and chromosome structure by human ORC2 [ORC5 ChECseq] 18 samples shares orc2, epigenetics, chromosome, structure
- GSE282575 Regulation of epigenetics and chromosome structure by human ORC2 [ORC1 ChECseq] 18 samples shares orc2, epigenetics, chromosome, structure
- GSE242143 DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex 75 samples shares orc2
- GSE240384 DNA methylation status determines the sensitivity of repeats to restriction by the HUSH-MORC2 complex [CUT&RUN] 42 samples shares orc2
- GSE336137 mTORC2-HIF-1β signaling creates a targetable sphingolipid vulnerability in lung cancer [Polysome-seq] 24 samples shares orc2
- GSE273434 Regulation of somatic hypermutation by higher-order chromatin structure 141 samples shares structure
- GSE246916 MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer 14 samples shares orc2
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.