GEO series
Gene expression analysis of human parotid salivary glands in cases of Mucoepidermoid Carcinoma via bulk RNA sequencing
GSE282430
Homo sapiens
Expression profiling by high throughput sequencing
28 samples
2025/05/16
GPL16791
Summary
Mucoepidermoid carcinoma (MEC) is the most frequently occurring salivary gland malignancy. Here, we investigated transcriptomic profiles of human adult salivary glands and MEC tumors to assess programs involved in MEC progression. MEC tumors were stratified by disease grade and CRTC1/MAML2 fusion status. The bioinformatics of our study will provide critical steps in elucidating salivary MEC progression and suggest a new candidates for targeted therapies in the treatment of high-grade MEC.
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Paper (PMID 40542202) ↗
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