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Transcription inhibition in early mouse embryos impacts transcriptome at 4-cell stage

GSE282667 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/01/20 Platform GPL21493
Summary
Mouse zygotes were treated with DRB to inhibit transcription activity, and early embryos were collected at 4-cell stage to examine transcriptome alteration by RNA-seq.
Published in
Deciphering transcription activity of mammalian early embryos unveils on/off of zygotic genome activation by protein translation/degradation
Zhang YR, Guo SM, Shi XY et al. · Cell reports 2025 · PMID 39823229 · doi:10.1016/j.celrep.2024.115215
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Also filed as BioProject PRJNA1188802. Searching any of these in the dataset finder brings you back here.

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