Comparative proteomic landscapes elucidate human preimplantation development and failure
RNA-seq (gene expression) · mouse · 24 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 24 samples: 6 conditions, mostly with about 4 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Comparative proteomic landscapes elucidate human preimplantation development and failureCell · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283213_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1191977 and SRA study SRP548293. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 24 samples.
How we read this: 6 replicated groups read from 24 sample titles; they account for 24 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8658070 NC_L2C_1 NC_L2C
- GSM8658071 NC_L2C_2 NC_L2C
- GSM8658072 NC_L2C_3 NC_L2C
- GSM8658073 NC_L2C_4 NC_L2C
- GSM8658074 NC_Mor_1 NC_Mo
- GSM8658075 NC_Mor_2 NC_Mo
- GSM8658076 NC_Mor_3 NC_Mo
- GSM8658077 NC_Mor_4 NC_Mo
- GSM8658078 Ttf1_KO_L2C_1 Ttf1_KO_L2C
- GSM8658079 Ttf1_KO_L2C_2 Ttf1_KO_L2C
- GSM8658080 Ttf1_KO_L2C_3 Ttf1_KO_L2C
- GSM8658081 Ttf1_KO_L2C_4 Ttf1_KO_L2C
- GSM8658082 Ttf1_KO_Mor_1 Ttf1_KO_Mo
- GSM8658083 Ttf1_KO_Mor_2 Ttf1_KO_Mo
- GSM8658084 Ttf1_KO_Mor_3 Ttf1_KO_Mo
- GSM8658085 Ttf1_KO_Mor_4 Ttf1_KO_Mo
- GSM8658086 Zfp622_KO_L2C_1 Zfp622_KO_L2C
- GSM8658087 Zfp622_KO_L2C_2 Zfp622_KO_L2C
- GSM8658088 Zfp622_KO_L2C_3 Zfp622_KO_L2C
- GSM8658089 Zfp622_KO_L2C_4 Zfp622_KO_L2C
- GSM8658090 Zfp622_KO_Mor_1 Zfp622_KO_Mo
- GSM8658091 Zfp622_KO_Mor_2 Zfp622_KO_Mo
- GSM8658092 Zfp622_KO_Mor_3 Zfp622_KO_Mo
- GSM8658093 Zfp622_KO_Mor_4 Zfp622_KO_Mo
- GSE272793 An atlas of small non-coding RNAs in Human Preimplantation Development (Mouse embryo RNA-seq) 132 samples shares preimplantation
- GSE274544 Single cell profiling reveals three endothelial to hematopoietic transitions with divergent isoform expression landscapes [scRNA-Seq] 1494 samples shares landscapes
- GSE268822 Transcriptional landscapes underlying Notch-induced lineage conversion and reprogramming of mammary cells 840 samples shares landscapes
- GSE232481 Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development [mouse scRNA-seq] 13 samples shares comparative
- GSE267993 ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development [scRNA-Seq] 96 samples shares preimplantation
- GSE272152 Optimizing murine sample sizes for RNA-seq studies revealed from large-scale comparative analysis 479 samples shares comparative
- GSE284053 Comparative transcriptomic rhythms in the mouse and human prefrontal cortex 59 samples shares comparative
- GSE205592 Obesity-instructed TREM2-high macrophages identified by comparative analysis of diabetic mouse and human kidney at single-cell resolution [scRNA-seq: DKD_mouse] 41 samples shares comparative
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.