Effect of IL-8 and VEGFA on polarization of tumor-associated macrophages
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MMP28 recruits M2-type tumor-associated macrophages through MAPK/JNK signaling pathway-dependent cytokine secretion to promote the malignant progression of pancreatic cancerJournal of experimental & clinical cancer research : CR · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283259_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1192969 and SRA study SRP548633. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE263382 Exogenous and endogenous serine modulate polarization of tumor-associated macrophages to influence development of nasopharyngeal carcinoma 6 samples shares tumor-associated, polarization, macrophages
- GSE329556 Xylosyltransferase-II deficiency rewires innate immune signaling and destabilizes polarization in human macrophages 24 samples shares polarization, macrophages
- GSE296472 Xenoline-polarized macrophages as a physiologically relevant in vitro model of tumor-associated macrophages in glioblastoma 20 samples shares tumor-associated, macrophages
- GSE282239 A new soluble CSF1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in mesothelioma. 12 samples shares tumor-associated, macrophages
- GSE262746 Nab-paclitaxel induces DNA damage and inhibits M2 polarization of macrophages to achieve radiosensitization of cholangiocarcinoma cells. 12 samples shares polarization, macrophages
- GSE307293 Fucosyltransferase 8-derived circular RNA drives M2 polarization of macrophages through ENO1-TNF signaling axis to promote lung cancer progression 12 samples shares polarization, macrophages
- GSE241007 Morusinol efficiently inhibits M2-like polarization of macrophages in vitro 12 samples shares polarization, macrophages
- GSE255490 Functional and mechanistic study of the inhibitory role of the antisense long non-coding RNA (IRF1-AS1) in regulating the transcriptional activity of IRF1 and M1 polarization of macrophages in ARDS. 9 samples shares polarization, macrophages
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.