GEO series
Effect of IL-8 and VEGFA on polarization of tumor-associated macrophages
GSE283259
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/02/26
GPL24676
Summary
We demonstrated in a previous study that IL-8 and VEGFA have a role in recruiting and polarizing macrophages. To fully confirm the specific mechanisms by which IL-8 and VEGFA secreted by pancreatic cancer cells affect macrophage polarization, we performed transcriptome sequencing on groups of macrophages after treatment of the co-culture system with anti-IL-8 and anti-VEGFA neutralizing antibodies.
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Paper (PMID 39972459) ↗
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