BCL11A is required for normal erythropoiesis [ATAC-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 24 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 24 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- BCL11A-deficient human erythropoiesis is impaired in vitro and after xenotransplantation into miceBlood advances · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283793_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1195593 and SRA study SRP550079. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 24 more — browse all 24 samples with per-sample file links →
- GSE274928 The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent 51 samples shares bcl11a, erythropoiesis
- GSE318082 BAF complexes maintain accessibility at stimulus-responsive chromatin and are required for transcriptional stimulus responses [ATAC-seq] 63 samples shares required, atac-seq
- GSE264030 BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation [ATAC-Seq] 9 samples shares atac-seq, normal
- GSE201822 CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis 60 samples shares erythropoiesis, required
- GSE201820 CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis [H2_HiC] 8 samples shares erythropoiesis, required
- GSE292753 Analysis of chromatin occupancy in erythroid cells by CUT&RUN following CRISPR editing of BCL11A enhancer 33 samples shares bcl11a
- GSE292698 Silencing of BCL11A by Disrupting Enhancer-Dependent Chromatin Insulation 95 samples shares bcl11a
- GSE291384 Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease 12 samples shares bcl11a
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.