GEO series
CFTR gene regulation in pancreatic duct, bile duct and sweat gland
GSE283992
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing
16 samples
2025/08/20
GPL21697GPL20301GPL34281
Summary
We examine cis-regulatory elements controlling expression of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in ductal eptihelial cells from pancreas, bile duct and sweat gland. Mutations in CFTR are associated with the inherited disorder cystic fibrosis. We identify several novel sites in addition to multiple elements seen in in other epithelial cell types.
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Paper (PMID 40785146) ↗
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