Histone H4 lysine 20 monomethylation is not a mark of transcriptional silencers
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 16 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Histone H4 lysine 20 monomethylation is not a mark of transcriptional silencersbioRxiv : the preprint server for biology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE284058_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1196916 and SRA study SRP550809. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 8 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8676837 S2 cells, H3K27me3 ChIP, replicate 1 S2 cells, H3K27me3 ChIP,
- GSM8676838 S2 cells, H3K27me3 ChIP, replicate 2 S2 cells, H3K27me3 ChIP,
- GSM8676839 S2 cells, H4K20me1 ChIP with Abcam ab9051 antibody, replicate 1 S2 cells, H4K20me1 ChIP…
- GSM8676840 S2 cells, H4K20me1 ChIP with Abcam ab9051 antibody, replicate 2 S2 cells, H4K20me1 ChIP…
- GSM8676841 S2 cells, H4K20me1 ChIP with Active Motif AB_2615074 antibody, replicate 1 S2 cells, H4K20me1 ChIP…
- GSM8676842 S2 cells, H4K20me1 ChIP with Active Motif AB_2615074 antibody, replicate 2 S2 cells, H4K20me1 ChIP…
- GSM8676843 S2 cells, H4K20me1 ChIP with Thermo Fisher MA5-18067 antibody, replicate 1 S2 cells, H4K20me1 ChIP…
- GSM8676844 S2 cells, H4K20me1 ChIP with Thermo Fisher MA5-18067 antibody, replicate 2 S2 cells, H4K20me1 ChIP…
- GSM8676845 S2 cells, ChIP INPUT, replicate 1 S2 cells, ChIP INPUT,
- GSM8676846 S2 cells, ChIP INPUT, replicate 2 S2 cells, ChIP INPUT,
- GSM9144895 K562 cells, H4K20me1 ChIP with Active Motif AB_2615074 antibody, replicate 1 K562 cells, H4K20me1 Ch…
- GSM9144896 K562 cells, H4K20me1 ChIP with Active Motif AB_2615074 antibody, replicate 2 K562 cells, H4K20me1 Ch…
- GSM9144897 K562 cells, H4K20me1 ChIP with Thermo Fisher MA5-18067 antibody, replicate 1 K562 cells, H4K20me1 Ch…
- GSM9144898 K562 cells, H4K20me1 ChIP with Thermo Fisher MA5-18067 antibody, replicate 2 K562 cells, H4K20me1 Ch…
- GSM9144899 K562 cells, ChIP INPUT, replicate 1 K562 cells, ChIP INPUT,
- GSM9144900 K562 cells, ChIP INPUT, replicate 2 K562 cells, ChIP INPUT,
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.