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Aberrantly Expressed RECQL4 Helicase Supports Proliferation and Drug Resistance of Human Glioma Cells and Glioma Stem Cells

GSE285044 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/12/26 Platform GPL18460
Summary
RECQL4 depletion in human glioma cells with genetic tools slightly impaired cell viability and DNA replication, induced changes in gene expression and increased sensitivity of glioma cells and glioma stem cells to chemotherapeutics
Published in
Shared and non-overlapping functions of RECQL4 and BLM helicases in chemotherapeutics-induced glioma cell responses
Wojnicki K, Wojtas B, Ciechomska IA et al. · BMC cancer 2025 · PMID 41023983 · doi:10.1186/s12885-025-14932-0
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Also filed as BioProject PRJNA1201109 and SRA study SRP552956. Searching any of these in the dataset finder brings you back here.

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