GEO series
Cannabis Use and Cannabidiol Modulate HIV-Induced Alterations in TREM2 Expression: Implications for Age-Related Neuropathogenesis
GSE285294
Homo sapiens
Expression profiling by high throughput sequencing
48 samples
2025/11/07
GPL24676
Summary
The study investigates the modulation of TREM2 and related gene expression in HIV- and HIV+ individuals with varying cannabis use patterns. RNA-seq data were obtained from monocyte-derived macrophages exposed to CBD, IL1B, and CBD+IL1B. This study aims to identify mechanisms by which CBD may alter neuroinflammatory processes relevant to TREM2, aging, and neuropathogenesis in people living with HIV.
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Paper (PMID 41998680) ↗
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