Bulk RNA sequencing of skin biopsies from psoriasis patients treated with Dead Sea climatotherapy
RNA-seq (gene expression) · human · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 30 samples: 30 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Early Neutrophil Activation in Psoriatic Skin at Relapse Following Dead Sea ClimatotherapyExperimental dermatology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285522_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1204294 and SRA study SRP554403. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 6 samples read as cases, 16 as controls.
How we read this: Read from 30 sample titles: 30 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8703796 Pt1 Baseline NL
- GSM8703797 Pt1 Baseline L
- GSM8703798 Pt1 End-of-treatment L
- GSM8703799 Pt1 Relapse
- GSM8703800 Pt3 NL Baseline
- GSM8703801 Pt3 L Baseline
- GSM8703802 Pt3 L End-of-treatment
- GSM8703803 Pt3 L Relapse
- GSM8703804 Pt4 Baseline NL
- GSM8703805 Pt4 Baseline L
- GSM8703806 Pt4 End-of-treatment L
- GSM8703807 Pt8 Baseline NL
- GSM8703808 Pt8 Baseline L
- GSM8703809 Pt8 End-of-treatment L
- GSM8703810 Pt8 L Relapse
- GSM8703811 Pt9 Baseline NL
- GSM8703812 Pt9 Baseline L
- GSM8703813 Pt9 End-of-treatment L
- GSM8703814 Pt9 L Relapse
- GSM8703815 Pt13 Baseline NL
- GSM8703816 Pt13 Baseline L
- GSM8703817 Pt13 End-of-treatment L
- GSM8703818 Pt13 L Relapse
- GSM8703819 Pt14 Baseline NL
- GSM8703820 Pt14 Baseline L
- GSM8703821 Pt14 End-of-treatment L
- GSM8703822 Pt19 Baseline NL
- GSM8703823 Pt19 Baseline L
- GSM8703824 Pt19 End-of-treatment L
- GSM8703825 Pt19 Relapse L
- GSE212476 Skin expression data from psoriasis patients treated with IL-17A inhibitor 40 samples shares psoriasis, treated, skin
- GSE311770 Minimally invasive 1 mm skin biopsies capture regional transcriptomic heterogeneity in vitiligo 105 samples shares biopsies, skin
- GSE290418 Bulk RNA-sequencing of human non-IBD enteroids treated with interferon-gamma (IFNγ) 12 samples shares treated, bulk
- GSE278330 Systemic IL-23 blockade downregulates IL-23 receptor-expressing Type 17 T-cell subsets and upregulates regulatory gene expression in myeloid cells in human psoriasis skin 63 samples shares psoriasis, skin
- GSE293037 Bulk transcriptome analysis of wildtype, TREM2 knockout, GPR34 knock-out or TREM2/GPR34 double knock-out iPSC-derived human microglia treated either with PBS or myelin. 32 samples shares treated, bulk
- GSE307519 bulk RNAseq of Ccd18-Co cell line treated with cytokine mix and/or epigenetic modulator 16 samples shares treated, bulk
- GSE272346 Late-stage tertiary lymphoid structures in hepatocellular carcinoma treated with neoadjuvant immune checkpoint blockade [bulk RNA-seq] 14 samples shares treated, bulk
- GSE295540 RNA-seq result of human skin derived from patients with psoriasis and healthy controls. 13 samples shares psoriasis, skin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.