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Foxa1 mutations co-opt nascent transcription factor networks in partnership with androgen receptor to enhance prostate tumorigenicity

GSE285574 Mus musculus Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing 38 samples 2026/01/01 GPL24247
Summary
Foxa1 mutants induce distinct transcriptomic and DNA accessibilities, prominent aberrant epithelial lineage gene expression, and enhance prostate tumorigenicity in vivo
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