GEO series
Single cell sequencing of VZV gE antigen-specific T cells with vaccination and age
GSE286045
Homo sapiens
Expression profiling by high throughput sequencing; Other
27 samples
2025/11/14
GPL24676GPL15520GPL30173
Summary
Generation and maintenance of a protective, durable T cell memory is incompletely understood. Here, we use single cell sequencing of VZV gE antigen-specific T cells (CD4+ or CD8+) after vaccination of younger or older adults to assess T cell heterogeneity and functional signatures.
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Paper (PMID 40502174) ↗
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