GEO series
Neuregulin-1β treatment augments compensatory remodeling and ameliorates cardiac function during pressure overload
GSE287122
Mus musculus
Expression profiling by high throughput sequencing
15 samples
2026/02/11
GPL19057
Summary
Purpose: This study investigates the impact of NRG1 on the cardiac adaptation to pressure overload and analyzes the underlying mechanisms. Methods: Male C57BL/6NRj mice underwent sham or transverse aortic constriction (TAC) surgery, received minipumps with either saline or NRG1 and were followed by echocardiography and BRB-seq analysis. Results: NRG1-induced functional improvement of the heart after TAC.
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