DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 18 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 18 samples: 8 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formationCell · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE287132_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1211158 and SRA study SRP557658. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 8 replicated groups read from 18 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8739225 HEK293T Control Input
- GSM8739226 HEK293T Control EGFP ChIP
- GSM8739227 FoxP2-EGFP Input Replicate 1 FoxP2-EGFP Input
- GSM8739228 FoxP2-EGFP EGFP ChIP Replicate 1 FoxP2-EGFP EGFP ChIP
- GSM8739229 FoxP2-EGFP Input Replicate 2 FoxP2-EGFP Input
- GSM8739230 FoxP2-EGFP EGFP ChIP Replicate 2 FoxP2-EGFP EGFP ChIP
- GSM8739231 FoxP2-R553H-EGFP Input Replicate 1 FoxP2-R553H-EGFP Input
- GSM8739232 FoxP2-R553H-EGFP EGFP ChIP Replicate 1 FoxP2-R553H-EGFP EGFP C…
- GSM8739233 FoxP2-R553H-EGFP Input Replicate 2 FoxP2-R553H-EGFP Input
- GSM8739234 FoxP2-R553H-EGFP EGFP ChIP Replicate 2 FoxP2-R553H-EGFP EGFP C…
- GSM8739235 FoxP2-R553H-MAFK-EGFP Input Replicate 1 FoxP2-R553H-MAFK-EGFP I…
- GSM8739236 FoxP2-R553H-MAFK-EGFP EGFP ChIP Replicate 1 FoxP2-R553H-MAFK-EGFP E…
- GSM8739237 FoxP2-R553H-MAFK-EGFP Input Replicate 2 FoxP2-R553H-MAFK-EGFP I…
- GSM8739238 FoxP2-R553H-MAFK-EGFP EGFP ChIP Replicate 2 FoxP2-R553H-MAFK-EGFP E…
- GSM8739239 FoxP2-R553H-Sox2-EGFP Input Replicate 1 FoxP2-R553H-Sox2-EGFP I…
- GSM8739240 FoxP2-R553H-Sox2-EGFP EGFP ChIP Replicate 1 FoxP2-R553H-Sox2-EGFP E…
- GSM8739241 FoxP2-R553H-Sox2-EGFP Input Replicate 2 FoxP2-R553H-Sox2-EGFP I…
- GSM8739242 FoxP2-R553H-Sox2-EGFP EGFP ChIP Replicate 2 FoxP2-R553H-Sox2-EGFP E…
- GSE257561 Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA 13 samples shares proteins, binding
- GSE100638 Large-scale tethering of RNA binding proteins discovers alternative splicing regulators 220 samples shares proteins, binding
- GSE290248 Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection 97 samples shares proteins, binding
- GSE290282 Large-scale tethered screen of RNA-binding proteins reveals novel regulators of poly(A) site selection [RNA-Seq] 92 samples shares proteins, binding
- GSE318822 MED26 facilitates Mediator–Pol II complex assembly and promotes nuclear stress body formation during heat stress 63 samples shares formation, assembly
- GSE268946 RNA-binding proteins DND1 and NANOS3 coordinately suppress SOX4 in processing bodies for restricting the entry of germ cell lineage 36 samples shares proteins, binding
- GSE325326 Codon-dependent regulation of mRNA translation and stability by ZC3H7A and ZC3H7B RNA-binding proteins 24 samples shares proteins, binding
- GSE293802 Integrative analysis of RNA binding proteins identifies DDX55 as a novel regulator of 3’UTR isoform diversity 18 samples shares proteins, binding
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.