MafB is a conserved transcriptional regulator of macrophage development and identity across tissues and species [CUT&Run]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 33 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 33 samples: 15 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- MafB is a conserved transcriptional regulator of macrophage development and functional identity across tissues and speciesImmunity · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE287346_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1212172 and SRA study SRP558116. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 30 samples.
How we read this: 15 replicated groups read from 33 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9267457 BMDM, IgG
- GSM9267458 BMDM WT, MafB1, Rep1 BMDM WT, MafB1,
- GSM9267459 BMDM WT, MafB1, Rep2 BMDM WT, MafB1,
- GSM9267460 BMDM WT, MafB2, Rep1 BMDM WT, MafB2,
- GSM9267461 BMDM WT, MafB2, Rep2 BMDM WT, MafB2,
- GSM9267462 BMDM WT, MafB3, Rep1 BMDM WT, MafB3,
- GSM9267463 BMDM WT, MafB3, Rep2 BMDM WT, MafB3,
- GSM9267464 BMDM KO, MafB1, Rep1 BMDM KO, MafB1,
- GSM9267465 BMDM KO, MafB1, Rep2 BMDM KO, MafB1,
- GSM9267466 BMDM KO, MafB2, Rep1 BMDM KO, MafB2,
- GSM9267467 BMDM KO, MafB2, Rep2 BMDM KO, MafB2,
- GSM9267468 BMDM KO, MafB3, Rep1 BMDM KO, MafB3,
- GSM9267469 BMDM KO, MafB3, Rep2 BMDM KO, MafB3,
- GSM9267470 LPM IgG
- GSM9267471 LPM WT, MafB1, Rep1 LPM WT, MafB1,
- GSM9267472 LPM WT, MafB1, Rep2 LPM WT, MafB1,
- GSM9267473 LPM WT, MafB2, Rep1 LPM WT, MafB2,
- GSM9267474 LPM WT, MafB2, Rep2 LPM WT, MafB2,
- GSM9267475 LPM WT, MafB3, Rep1 LPM WT, MafB3,
- GSM9267476 LPM WT, MafB3, Rep2 LPM WT, MafB3,
- GSM9267477 LPM KO, MafB1, Rep1 LPM KO, MafB1,
- GSM9267478 LPM KO, MafB1, Rep2 LPM KO, MafB1,
- GSM9267479 LPM KO, MafB2, Rep1 LPM KO, MafB2,
- GSM9267480 LPM KO, MafB2, Rep2 LPM KO, MafB2,
- GSM9267481 LPM KO, MafB3, Rep1 LPM KO, MafB3,
- GSM9267482 LPM KO, MafB3, Rep2 LPM KO, MafB3,
- GSM9267483 MDM, IgG
- GSM9267484 MDM, MafB1, Rep1 MDM, MafB1,
- GSM9267485 MDM, MafB1, Rep2 MDM, MafB1,
- GSM9267486 MDM, MafB2, Rep1 MDM, MafB2,
- GSM9267487 MDM, MafB2, Rep2 MDM, MafB2,
- GSM9267488 MDM, MafB3, Rep1 MDM, MafB3,
- GSM9267489 MDM, MafB3, Rep2 MDM, MafB3,
- GSE127465 Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species 40 samples shares conserved, species, across
- GSE324505 Cross-Species Transcriptomic Integration Reveals a Conserved, MIRO1-Mediated Macrophage-to-T Cell Signaling Axis Driving Immunosuppression in Glioma 12 samples shares macrophage, conserved, species
- GSE266329 Co-culture CRISPR screens reveal ATG9A as a regulator to macrophage-mediated cytotoxicity in cancer 8 samples shares macrophage, regulator
- GSE253161 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease [NIH-3T3_K562_RNA_without_blocking] 1 samples shares macrophage, regulator
- GSE286290 Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders [CUT&RUN] 81 samples shares cut
- GSE172296 A myeloid maturation program initiated by nucleotide depletion during S phase [Cut & Run] 47 samples shares cut
- GSE303627 MYST acetyltransferases are a targetable therapeutic vulnerability in SETBP1-mutant leukemia [CUT&Run] 46 samples shares cut
- GSE249799 scNanoSeq-CUT&Tag: a long-read single-cell CUT&Tag sequencing method for efficient chromatin modification profiling within individual cells 46 samples shares cut
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.