GEO series
Aging and the pathophysiology of pulmonary Mycobacterium avium complex (MAC) disease
GSE287501
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/03/18
GPL19057
Summary
We infected 18-month-old mice (old mice) and 9-week-old mice (young mice) with 1 × 10⁷ CFU of Mycobacterium avium via the respiratory tract for comparison analysis. Two months post-infection, both bacterial loads and mortality rates were significantly higher in old mice compared to young mice. RNA-seq analysis of lung tissues were performed.
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Paper (PMID 41822512) ↗
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