GEO series
Stepwise activation of primary human memory CD4+ T cells
GSE288509
Homo sapiens
Expression profiling by high throughput sequencing
21 samples
2025/02/11
GPL24676
Summary
CD4+ T cells are a highly differentiated cell type that maintain enough transcriptomic plasticity to cycle between activated and memory statuses. We generated RNA-seq libraries from T-cells harvested from three independent blood donors under three separate conditions: unstimulated fresh ex vivo, IL-2 only stimulated and TCR+CD28+IL-2 stimulated, conferring increasingly stronger activation signals. .
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Paper (PMID 40018706) ↗
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