GEO series
Neurons undergo IFNγ-driven persistent epigenetic shifts and synaptic remodeling in the inflamed brain [RNA-Seq]
GSE288606
Mus musculus
Expression profiling by high throughput sequencing
52 samples
2025/12/23
GPL21103
Summary
Our study provides novel evidence that neuronal intrinsic epigenetic changes are established as a consequence of cytotoxic T cell-mediated immune attacks and persist long after the resolution of the inflammatory process and associate to long lasting synaptic loss
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Paper (PMID 41448185) ↗
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